新加坡南洋理工大学赵彦利教授学术报告会通知

2021年04月09日 17:20  点击:[]

报告题目:Supramolecular Nanomedicine for Cancer Theranostics

报告人:赵彦利 教授

报告时间:2021415日(星期10:00

线上腾讯会议:https://meeting.tencent.com/s/DSlwwhvvo3Zy

会议ID: 273 493 501

线下地点:长安校区启翔楼233会议室

邀请人:冯涛 副教授

报告简介:

Responsive supramolecular systems have recently gained enormous attention in the areas of bioimaging and therapeutics on account of their ability to deliver biologically active molecules with spatial and temporal control through the means of regulated stimuli. We have developed several responsive multifunctional nanosystems for targeted bioimaging and controlled drug delivery in cancer treatment. To overcome the issues of photon scattering and low optical response in biological tissues, we have fabricated integrated nanoparticles as exogenous contrast agents for enhancing the capability of bioimaging modalities, discovered a strategy of using porous nanoparticles to prevent undesired aggregation of biological dyes for enhanced bioimaging, and developed self-assembled nanoparticles for photo-tunable bioimaging in order to visualize different stages of cell evolvement. In the follow-up research, we have synthesized several types of responsive nanosystems for fluorescent, two-photon, three-photon, and photoacoustic bioimaging-guided therapy. These responsive nanosystems could generally perform several important roles: (1) nanocarriers for drug delivery, (2) triggers for drug release, (3) chromophores for cell imaging, and (4) switchable fluorophores for real-time monitoring of drug release. The responsive bioimaging and therapeutics strategy developed by us could potentially be applied to existing drugs or experimental compounds that would benefit from longer circulation time or better targeting for next-generation cancer theranostics.

报告人简介:

赵彦利,新加坡南洋理工大学数理学院、化学和生物医学工程学院、以及材料科学和工程学院教授,数理学院助理院长。于南开大学获得本科和理学博士学位,博士导师为刘育教授。随后在美国加州大学洛杉矶分校以及西北大学从事博士后研究,师从诺贝尔化学奖得主Sir Fraser Stoddart教授。主要从事合成化学和材料科学前沿交叉领域的研究。研究兴趣集中于新型自聚集材料的设计和制备,及其在生物医学、催化和绿色能源等领域的应用开发。共发表SCI论文400篇,h指数81先后获得新加坡国家研究基金会Fellowship (2010)《麻省理工学院技术评论》评选的杰出青年创新人物(新加坡2012)亚太光化学学会青年科学家奖(2016)、美国化学会ACS Applied Materials & Interfaces青年研究员奖(2017)新加坡国家研究基金会Investigatorship (2018)、科睿唯安全球高被引科学家(2018-2020)等荣誉和奖励。担任ACS Applied Nano Materials执行主编。


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