鲁神赐|LU Shen-Ci

2019年03月19日 12:11  点击:[]

联系方式

Email:  iamsclu@nwpu.edu.cn

办公地点:西安市友谊西路127号,西北工业大学老图书馆

教育经历

2018.11- 至今 西北工业大学 柔性电子研究院 教授

2017.10-2018.11 高级研究员 新加坡国立大学 导师: 赵宇教授

2011.10-2017.9  研究员  新加坡国立大学 导师: 赵宇教授

2008.9-2011.6  博士学位 兰州大学 功能有机分子化学国家重点实验室 导师: 张炜教授

2005.9-2008.6  硕士学位  兰州大学 功能有机分子化学国家重点实验室 导师: 张炜教授

研究方向

不对称催化、有机小分子催化、光催化

工作经历

20118月赵宇(Assistant professor)在新加坡国立大学开展独立工作。10月加入其课题组。帮助组建实验室以及开创氮杂卡宾(NHC)课题. 两个博士生(Poh Sibei 20141月跟 Ong Jun-Yang 20168月)先后加入该氮杂卡宾课题组。期间指导了多名本科生毕业论文。多名学生获得优秀本科毕业论文称号。

2011.10-2017.10: 研究员 (Research Fellow) 新加坡国立大学 化学系 赵宇教授
2017.10-至今: 高级研究员 (Senior Research Fellow) 新加坡国立大学 化学系 赵宇教授

主要学术成绩

长期开展小分子不对称催化和光环化反应研究,近年以第一作者或通讯作者发表J. Am. Chem. Soc.Nat. Commun.,  Angew. Chem. Int. Ed. 4篇, Org. Lett. 2篇, Chem. Eur. J. J. Org. Chem. Adv. Synth. Catal.等国际著名期刊上发表研究性论文17篇。

基金资助

2018年获西北工业大学翱翔海外青年学者资助

代表性论文

[1] Shenci Lu, Jun-Yang Ong, Hui Yang, Si Bei Poh, Xi Liew, Chwee San Deborah Seow, Ming Wah Wong* and Yu Zhao*, Diastereo- and Atroposelective Access to Bridged Biaryls Bearing an Eight-Membered Lactone through an Organocatalytic Cascade” J. Am. Chem. Soc. 2019, 141, 17062-17067. (IF: 14.695)

[2] Shenci Lu, Shawn Voon Hwee Ng, Kaitlyn Lovato, Jun-Yang Ong, Si Bei Poh, Xiao Qian Ng, László Kürti* and Yu Zhao*, “Practical Access to Axially Chiral Sulfonamides and Biaryl Amino Phenols via Organocatalytic Atroposelective N-Alkylation” Nat. Commun. 2019. 10, 3061. (Highlighted by X-MOL) (IF: 11.878)

[3] Shenci Lu, Jun-Yang Ong, Si Bei Poh, Terence Tsang and Yu Zhao* “Transition Metal-Free Decarboxylative Propargylic Substitution/ Cascade Cyclization with Azolium Enolates or Acyl Anions”, Angew. Chem. Int. Ed. 2018, 57, 5714-5719. (Highlighted by Synfacts 2018, 14, 797and X-MOLand X-MOL and X-MOL). (IF: 12.1)

[4] Si Bei Poh, Jun-Yang Ong, Shenci Lu* (通讯作者) and Yu Zhao* “Highly Regio- and Stereodivergent Access to 1,2-Amino Alcohols or 1,4-Fluoro Alcohols by NHC-Catalyzed Ring Opening of Epoxy enals”. Angew. Chem. Int. Ed. 2018, 57, 1645-1649. (IF: 12.1)

[5] Shenci Lu, Si Bei Poh, and Yu Zhao*. “Kinetic Resolution of 1,1’-Biaryl-2,2’-Diols and Amino Alcohols through NHC-Catalyzed Atroposelective.”, Angew. Chem. Int. Ed. 2014, 53, 11041 –11045. (Highlighted by Synfacts 2014, 10, 1208). (IF: 12.1, 他引42 )

[6] Shenci Lu, Si Bei Poh, Woon-Yew Siau, and Yu Zhao*. “Kinetic Resolution of Tertiary Alcohols: Highly Enantioselective Access to 3-Hydroxy-3-Substituted Oxindoles.”, Angew. Chem. Int. Ed. 2013, 52, 1731 –1734. (Highlighted by Synfacts 2013, 9, 332). (IF: 12.1, 他引47 )

[7] Shenci Lu, Si Bei Poh, Zi-Qaing Rong* and Yu Zhao*. NHC-Catalyzed Atroposelective Acylation of Phenols: Access to Enantiopure NOBIN Analogs by Desymmetrization ” Org. Lett. 2019, 21, 6169-6172. (IF: 6.555)

[8] Shenci Lu, Xiaoxiao Song, Si Bei Poh, Hui Yang, Ming Wah Wong* and Yu Zhao.* “Access to Enantiopure Triarylmethanes and 1,1-Diarylalkanes by NHC-Catalyzed Acylative Desymmetrization.” , Chem. Eur. J. 2017, 23, 2275 – 2281. (IF: 5.31) 

[9] Shenci Lu, Si Bei Poh, Woon-Yew Siau, and Yu Zhao * “Kinetic Resolution of 3-Hydroxy-3-Substituted Oxindoles through NHC Catalyzed Oxidative Esterification.”, Synlett. 2013, 24, 1165–1169.

[10] Shenci Lu, Ren Wang, Yi Yang, Yang Li, Zongjun Shi, Wei Zhang*, and Zhifeng Tu. Photoinduced Intramolecular Halogen Atom-Transfer Addition of 3-Acyl-2-haloindoles to Phenylethynes and 1,5-Hydrogen Shift / Decarbonylation Cyclization vs Electrocyclic Deacylation Cyclization. J. Org. Chem. 2011,76, 5661–5669. 

[11] Shen-Ci Lu, Shi-Chao Wei, Wei-Xia Wang, Wei Zhang* , and Zhifeng Tu. One-pot Synthesis of Fused Benzo[c]carbazoles by Photochemical Intramolecular Annulation of 3-Acyl-2-haloindoles with Tethered Styrenes. Eur. J. Org. Chem. 2011, 5905–5910. 

[12] Shen-Ci Lu, Xiao-Yong Duan, Zong-Jun Shi, Bing Li, Yu-Wei Ren, Wei Zhang*, Yong-Hui Zhang, and Zhi-Feng Tu. Photoinduced Intramolecular Addition of 3-Acyl-2-haloindoles to Alkenes. Org. Lett. 2009, 11, 3902-3905.

[13] Shen-Ci Lu, Xi-Xia Zhang, Zong-Jun Shi, Yu-Wei Ren, Bing Li, and Wei Zhang*. Intramolecular Photochemical Cross-coupling Reactions of 3-Acyl-2-haloindoles and 2-Chloropyrrole-3-carbaldehydes with Substituted Benzenes. Adv. Synth. Catal. 2009. 3512839-2844.

[14] Shen-Ci Lu, Wei-Xia Wang,  Pan-Liang Gao, Wei Zhang*, Zhi-Feng Tu. Photoinduced chlorine atom-transfer cyclization/photohydrolysis of 3-acyl-2-chloro-N-(omega-phenylalkynyl)pyrroles: a one-pot synthesis of benzoyl-substituted fused pyrroles. Org. Biomol. Chem., 2012,10, 232-235.

[15] Shenci Lu, Wei Zhang*, Jinhui Pan, Jie Zhang. Synthesis of Pyrazolo[4,3-c]quinolin-4-ones and Indolo[3,2-c]quinolin-6-ones by the Photocyclization of o-Chloroheteroaryl N-Arylcarboxamides. Synthesis. 2008, 10, 1517-1522.

[16] Cailin Wang, Wei Zhang*, Shenci Lu, Jingfei Wu, Zongjun Shi. Chem Comm. 2008, 5176-5178.

[17] Zongjun Shi, Yuwei Ren, Bing Li, Shenci Lu, Wei Zhang*. Chem Comm. 2010, 46, 3973-3975.

专著

Shenci Lu, Si B. Poh, Jun Y. Ong, and Yu Zhao. N-Heterocyclic Carbenes in Organocatalysis. Chapter 10, NHC-Catalyzed Kinetic Resolution, Desymmetrization,  and DKR Strategies. pg 287-308  Published 2019 byWiley-VCH Verlag GmbH & Co. KGaA.





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